This study was conducted to evaluate the mitigative effect of Glycyrrhiza glabra and Zingiber Officinale on the productive performance, physiological and histopathological picture of Oreochromis Niloticus. 1800 fingerlings were randomly distributed into four experimental groups; three replicates each, the stocking rate was 150 fingerling /replicate, average initial
weight were 17.5 ±0.109 g and the average initial length 10.13± 0.37 cm/fish. Group one fed on the basal diet, group two fed on basal feed fortified by ginger extract 5ml/kg, group three taken basal feed plus liquorice 4ml/kg, and the fourth group was received basal feed treated ginger and liquorice 2.5ml/kg +2ml/kg respectively. After four month data were collected;
Productive performance includes body weight, body length, feed intake, feed conversion ratio, mortality rate. Physiological and blood biochemical parameters includes RBCs count, WBCs count, Hb concentration, PCV %, differential leukocytic count, serum proteins (g /dl), serum albumin (g /dl), serum globulins, albumin/globulin ratio and creatinine (mg/dl) finally tissue specimen from, gills, intestine and liver of fish were collected for histopathological examination. The obtained results revealed a high significance difference between the treatments. Group four recorded higher body weight 237.21± 5.6 g followed by group three 211.03±3.2 g, and the lowest body weight was in control group 190.77 ± 3.88 g. Lower feed
conversion ratio recorded in group four 1.82 ± 0.03 g, Highest level of hemoglobin conc., white blood cell count, and total leukocytic count recorded in group four followed by group two. Base up on results obtained we concluded that using one Ginger and or liquorice herbal extract has positive effect on performance, blood biochemical and histological picture in the
Oreochromis niloticus.