The aim of this study was to conduct an investigation into the effect of palm dates on innate immunity of broiler. One hundred twenty broiler chicks were portioned out in 6 experimental groups for 5 weeks. The experimented chicks received palm date in diet and 10 birds from each group were oral administration with challenging bacteria E.coli, S. Typhimurium,
C. perfringens, P. multocida and A. paragallinarum. 5 randomly serum, spleen and intestinal samples were collected from each group weekly before and after the bacterial challenge for evaluation of innate and acquired immunity of the challenged birds. IL-6, IFN-γ and IgA in serum of in control group were the lowest in all weeks compared to other groups except in
week two IgA value was similar to C. perfringens and higher than S. Typhimurium group in week four. E.coli group was lower than the other challenged groups in IL-6, IFN-γ and IgA in all weeks except IL-6 in week five and six it was higher than S. Typhimurium group and A. paragallinarum group, IFN-γ was similar to C. perfringens group and P. multocida group
in first and second week and IgA value was higher than S. Typhimurium group in week three, four and five. C. perfringens group was the highest in IL-6 in week three, four and five and the highest of IFN-γ in week three. IgA values of A.paragallinarum group were higher than other groups in week six. P. multocida group was the highest IgA in all weeks  except in week one and six; it was the highest value of IFN-γ in week four and six