Nonvariceal upper gastrointestinal bleeding (NVUGIB) is an important condition that continues to exert a significant burden on healthcare systems. Despite improvement in the medical and endoscopic therapies for NVUGIB, the morbidity and mortality of this condition remain unchanged, largely related to the increasing age and comorbidities of the affected population. Several endoscopic modalities are available to manage bleeding lesions, but a significant proportion of patients suffer from primary failure in achieving hemostasis or rebleed after initial successful hemostasis, which carry worsened outcomes for patients. Recently, the management of NVUGIB has seen significant evolution with the introduction of several novel endoscopic tools including cap-mounted clips. These clips have been utilized in managing patients with NVUGIB as a primary or rescue therapy with promising results. Several randomized controlled studies have been published in recent years addressing the role of such clips yielding overall favorable outcomes. In this article, we will review the recent updates in the role of cap-mounted clips in the management of NVUGIB, while identifying current limitations in the evidence that are pertinent to the adoption of this hemostatic modality by clinicians in routine practice.