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257514

Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat

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Last updated: 05 Jan 2025

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Abstract

This study evaluated the protective and ameliorative role of date palm pollen and vitamin C against bisphenol- A ( BPA ) induced gastric structure toxicity in rats. control rats received only food and water, Second group administrated BPA ( 30 mg/kg b.wt. ). Third group was given DPP (100 mg/kg b.wt.).Fourth group was given Vit. C (160 mg/kg b.wt.). Fifth group was given DPP 12 hrs before administration of DPP, while the sixth group was given BPA 12 hrs before administration of BPA. The seventh group was given Vit. C 12 hrs before administration of BPA, whereas the eighth group was given BPA 12 hrs before administration of vit. C. The ninth group was given DPP combined with Vit. C 12 hrs before administration of BPA.BPA induced histopathological changes in the stomach indicated by congestion at the vasculatureand edema of the submucosal layer of the non-glandular part, and congestion of the blood vessels at the muscular layer of the glandular part. However, administration of each DPP and vitamin C before and after BPA, or combined with each other before BPA, restored the normal histological structure of the stomach. So, this study revealed that DPP and Vit. C protected and ameliorated gastric structure against BPA toxicity via their antioxidant activities.

DOI

10.21608/sjsci.2022.157065.1023

Keywords

Bisphenol-A, gastric tissue, date palm pollen, vitamin c, male rats

Authors

First Name

Mohamed

Last Name

El-Sayed

MiddleName

-

Affiliation

Zoology Department, Faculty of Science, Sohag University, Sohag, Egypt

Email

m_farag6000@yahoo.com

City

-

Orcid

-

First Name

Sarry

Last Name

Abdel-Ghaffar

MiddleName

-

Affiliation

Department of Pathology and Clinical pathology, Veterinary medicine Faculty, Assiut University

Email

sary64@windowslive.com

City

-

Orcid

-

First Name

Tito

Last Name

Habib

MiddleName

-

Affiliation

Department of Zoology, Faculty of Science, Sohag University, Sohag, 52824, Egypt

Email

titohabib99@science.sohag.edu.eg

City

-

Orcid

0000-0003-1852-3558

First Name

Mohamed

Last Name

El-Sayed

MiddleName

Ali

Affiliation

Department of Zoology, Faculty of Science, Sohag University, Sohag, 52824, Egypt

Email

mo_ali985@yahoo.com

City

-

Orcid

-

Volume

7

Article Issue

3

Related Issue

35432

Issue Date

2022-09-01

Receive Date

2022-08-18

Publish Date

2022-09-01

Page Start

183

Page End

187

Print ISSN

2357-0938

Online ISSN

2974-4296

Link

https://sjsci.journals.ekb.eg/article_257514.html

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https://sjsci.journals.ekb.eg/service?article_code=257514

Order

257,514

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Regular Articles

Type Code

2,359

Publication Type

Journal

Publication Title

Sohag Journal of Sciences

Publication Link

https://sjsci.journals.ekb.eg/

MainTitle

Protective and ameliorative role of date palm pollen and vitamin C against gastric toxicity induced by bisphenol-A in male albino rat

Details

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Article

Created At

23 Jan 2023