The present work was conducted to evaluate the influence of replacing fish meal with agriculture residues on the water quality parameters, biochemical composition, and growth performance of grass carp (Ctenopharyngodon idella). A total of 400 grass carp (Ctenopharyngodon idella) with an average body weight of 100.1±1 g were used in the present study. The fish were randomly divided into 4 groups (100 fish/pond). A basal control diet was formulated to fulfil the nutrient requirements of the fish that contained 25% crude protein (CP). The other 3 diets (treatment diets) were alfalfa diet, peanut leaves diet, and a mixture of alfalfa and peanut leaves diet. The fish were fed six days per week for 90 days at a daily feeding of 3% of the estimated fish-weight of the total biomass of the fish with twice daily feeding at 8.00 am and 4.00 pm.  Water quality parameters were found within a suitable range for fish production in the present experiment. Crude protein and moisture contents were the best when fish fed Alfalfa.  Ash content showed significant differences among the tested diets. In addition, the lowest retention of crude protein and moisture at fish fed Peanut leaves.
The obtained data showed that growth performance was significantly affected by using alternative diet (Alfalfa, Peanut leaves and Alfalfa + Peanut leaves). As well as fish reared on Alfalfa + Peanut leaves showed the highest final weight (225.3 g), weight gain (91.6 g). While fish reared on Alfalfa showed lowest final weight (202.6 g), weight gain (79.3 g). It is observed that the best of FCR was recorded in fish fed on Alfalfa + Peanut leaves (1.7) followed by fish fed on Peanut leaves (1.9), whilst the worst FCR (2.1) was obtained in fish fed Alfalfa compared to the control group (1.3). Fish reared fed commercial diet exhibited the lowest significant survival percent (88.2%). Significant elevation was observed in the survival rate of the fish fed on alternative diet (Peanut leaves 88.6, Alfalfa + Peanut leaves 83.6 and Alfalfa 99.1) compared to the control.  The result from this study indicates that alfalfa and groundnut leaves can be used as fish food in the diet of grass carp without adversely affecting growth efficiency and whole body composition.