The Egyptian Holding Company for Water and Wastewater and its affiliated companies have started a programme to develop riverbank filtration (RBF) sites in all Egyptian governorates trying to cover all hotspots due to drinking water shortage in these areas. The paper gives an overview of water quality parameters as a result of RBF, during continuous operation in Sohag, Upper Egypt. Two RBF sites were developed in Sohag. Whereas water quality changes during RBF, redox-zonation and removal rates have been discussed by many authors, little information is available on the initial phase of new RBF schemes. The new RBF sites in Upper Egypt can provide low-cost, green and sustainable drinking water supply for many studied hotspot areas.Between 2018 and 2021, significant changes were observed for total dissolved solids, chloride, sulfate, iron, manganese and ammonium concentrations, and bacterial counts. The results showed that RBF   wells should be operated continuously, to maintain the advantage of lower Fe and Mn concentrations achieved by the wash-out effect in the aquifer zone between the riverbank and the RBF wells. A Water Safety Plan Approach was applied to the site to reduce the opportunity of hazards from the surroundings.