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233419

Synthesis of Some New Thieno[2,3-b]thiophene Derivatives and Prediction their Biological Activity by PASS INET

Article

Last updated: 29 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Chemistry

Abstract

A series of thieno[2,3-b] thiophene moiety-containing bis-barbituric 2a,b and bis-pyrazoles 3-4a–b  derivatives were synthesized and predict their biological activity using PASS INET. According to obtanied data the most frequently predicted, which they showed high biological activity predicted for a potential compound with the highest probability are oxidoreductase inhibitor, chemosensitizer, potassium channel large-conductance Ca-activated activator, Cystinyl aminopeptidase inhibitor and Neurotransmitter uptake inhibitor.

DOI

10.21608/sjsci.2022.233419

Keywords

Thieno[2, 3-b]thiophene – Pass predicition – Azo dye – PASS INET

Authors

First Name

Mahmoud Abd El Aleem

Last Name

El- Remailya

MiddleName

Ali Ali

Affiliation

Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

Email

msremaily@yahoo.com

City

-

Orcid

0000-0002-3591-0077

First Name

Elders

Last Name

Shokr

MiddleName

Kh.

Affiliation

Physics Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

Email

-

City

-

Orcid

-

First Name

H.

Last Name

Abdel-Ghany

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

Email

-

City

-

Orcid

-

First Name

Moumen

Last Name

Kamel

MiddleName

S.

Affiliation

Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

Email

-

City

-

Orcid

-

First Name

Omar. M.

Last Name

Elhady

MiddleName

-

Affiliation

Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Soliman

MiddleName

M.

Affiliation

Chemistry Department, Faculty of Science, Sohag University, Sohag 82524, Egypt

Email

-

City

-

Orcid

-

Volume

7

Article Issue

2

Related Issue

33485

Issue Date

2022-05-01

Receive Date

2022-01-24

Publish Date

2022-05-01

Page Start

9

Page End

13

Print ISSN

2357-0938

Online ISSN

2974-4296

Article File

SJSCI_Volume 7_Issue 2_Pages 9-13.pdf

PDF . 810.2kB

Link

https://sjsci.journals.ekb.eg/article_233419.html

Detail API

https://sjsci.journals.ekb.eg/service?article_code=233419

Order

233,419

Type

Regular Articles

Type Code

2,359

Publication Type

Journal

Publication Title

Sohag Journal of Sciences

Publication Link

https://sjsci.journals.ekb.eg/

MainTitle

Synthesis of Some New Thieno[2,3-b]thiophene Derivatives and Prediction their Biological Activity by PASS INET

Details

Type

Article

Created At

23 Jan 2023