Background: Management of patients following coronary artery bypass graft (CABG) surgery include intake of different types of medications adherence is an important issue that affect patients' health outcome. Aim: To assess level of medication adherence in coronary artery bypass graft (CABG) patients. A descriptive study design was used. Setting: This study was carried out at the cardiac follow-up clinic in Suez Canal University Hospitals and Nasser institute hospital for research and treatment services. Sample: The study was implemented on 85 patients post CABG surgery. Tools: two tools were used: tool I: interview questionnaire to assess demographic data, clinical history, tool II: Eight-item Morisky Medication Adherence Scale to assess patient's adherence level of medications. Results: the study showed that the total adherence mean scores among the studied patient was high in using Antihypertensive drugs (6.56±1.07), followed by anticoagulants drugs (6.51±1.21), then antihyperlipidemic drugs (6.50±1.20). Conclusion: the total adherence mean scores among the studied patient was high in using Antihypertensive drugs, followed by anticoagulants drugs, then antihyperlipidemic drug. Recommendations: implementing study to evaluate effect of medication adherence on quality of life in patients with CABG.