Beta
ManageSearchChatDiscover
233142

Role of stem cells in decreasing renal failure in rats

Article

Last updated: 29 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Genetic Evolution and its impact on the production efficiency of the animal
Studies on Sequence Gene mutations and monitoring the causes of epidemic diseases

Abstract

Stem cells are homogenous cells able-to-proliferate and differentiate producing almost all types of cells. They can yield a great number of differentiated functional cells creating the tissue after hurt. Stem cell therapy is a recent type of intervention strategy that is introduced-to-treat-a-specific-illness. Renal failure is one of the greatest common reasons of morbidity-and-mortality-all-over-the-world. Treatment options of chronic renal failure (CRF) mainly involve renal transplantation and blood dialysis. Kidney transplantation is limited by shortage of donors while dialysis is-associated---with-- several-socioeconomic-problems-for-the-patients.-In this study we tried to estimate the use of stem cells for antagonizing induced renal failure via apoptotic parameters. The animals were classified into five groups which received chemotherapeutic drug (cisplatin) to induce kidney damage, tissue and blood samples were collected. The oxidative content measured by glutathione. The serum urea, creatinine and IL18 biomarkers levels were decreased significantly. This confirms that under the conditions of this study, stem cells can heal the renal damage made by cisplatin in rats. 

DOI

10.21608/ejceh.2020.233142

Authors

First Name

Muhammad

Last Name

Mahammoud

MiddleName

A.

Affiliation

GEBRISadat University. Egypt

Email

-

City

-

Orcid

-

First Name

Samir

Last Name

El-Masry

MiddleName

A.

Affiliation

Biochemistry dept, GEBRISadat University. Egypt

Email

-

City

-

Orcid

-

First Name

,Sherief

Last Name

El-Sherbini

MiddleName

-

Affiliation

Biochemistry dept., GEBRSadat University, Egypt

Email

-

City

-

Orcid

-

First Name

Sayed

Last Name

Bakry

MiddleName

-

Affiliation

Experimental Biology dept., faculty of scienceAl-Azhar University, Cairo, Egypt

Email

-

City

-

Orcid

-

Volume

6

Article Issue

1

Related Issue

33435

Issue Date

2020-05-01

Receive Date

2022-04-24

Publish Date

2020-05-01

Page Start

1

Page End

18

Online ISSN

2357-1039

Article File

EJCEH_Volume 6_Issue 1_Pages 1-18.pdf

PDF . 809.2kB

Link

https://ejceh.journals.ekb.eg/article_233142.html

Detail API

https://ejceh.journals.ekb.eg/service?article_code=233142

Order

233,142

Type

Scientific and Research

Type Code

2,340

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry and Environmental Health

Publication Link

https://ejceh.journals.ekb.eg/

MainTitle

Role of stem cells in decreasing renal failure in rats

Details

Type

Article

Created At

23 Jan 2023