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241065

Effect of Glyphosate on Male Fertility, Cytogenicity and Biochemical Parameters in Rats

Article

Last updated: 29 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Effect of drugs and insecticides on animal health

Abstract

Oral administration of round up in rats doses of 49 and 490 mg/kg b.wt. daily for 65 successive days respectively, significantly decreased the weight of sexual organs, sperm cell concentration and sperm motility while the sperm abnormalities were increased. The levels of creatinine, cholesterol, uric acid and bilirubin in serum were significantly increased.Round up significantly increased the activities of serum AST, ALT and AP. The tested herbicide showed mutagenic potential as measured by a positive response in the micronucleus assay. The small dose tested caused slight toxicity to the bone marrow proliferation as determined by insignificant increased rate of bone marrow cells while the large dose significantly increased the rate of bone marrow proliferation as determined by the increase the rate of ratio in tested groups over that of the control. 

DOI

10.21608/ejceh.2018.241065

Authors

First Name

K.

Last Name

ElEkhnawy

MiddleName

E.

Affiliation

Animal Health Research Institute

Email

-

City

-

Orcid

-

First Name

KM

Last Name

Abd-Elazzim

MiddleName

-

Affiliation

Animal Health Research Institute

Email

-

City

-

Orcid

-

First Name

Ragaa

Last Name

Faisal

MiddleName

asr

Affiliation

EFSA on biologicals

Email

-

City

-

Orcid

-

First Name

Nahla

Last Name

kotb

MiddleName

SH.

Affiliation

EFSA on biologicals

Email

-

City

-

Orcid

-

Volume

4

Article Issue

2

Related Issue

33423

Issue Date

2018-11-01

Receive Date

2022-06-02

Publish Date

2018-11-01

Page Start

13

Page End

20

Online ISSN

2357-1039

Article File

EJCEH_Volume 4_Issue 2_Pages 13-20.pdf

PDF . 375.2kB

Link

https://ejceh.journals.ekb.eg/article_241065.html

Detail API

https://ejceh.journals.ekb.eg/service?article_code=241065

Order

241,065

Type

Scientific and Research

Type Code

2,340

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry and Environmental Health

Publication Link

https://ejceh.journals.ekb.eg/

MainTitle

Effect of Glyphosate on Male Fertility, Cytogenicity and Biochemical Parameters in Rats

Details

Type

Article

Created At

23 Jan 2023