ABSTRACT: Comparative assessments of drinking water quality and wastewater were carried out at different cities of El Gharbia Governorate, Egypt. The results showed that the presence of bacterial contamination was found in drinking water samples. These bacteria contain enteric and pathogens genera when identified. Therefore, in this study was carried out to compare the levels, total counts and identification bacteria of wastewater at the same cities of previous collected drinking water samples. The results wastewater showed that the highest number of total bacteria counts were found in summer season at El mehala Elkobra. And the total bacterial counts were tested on different selective media. The bacterial isolates belonging to: Aeromonas sobria, Staphylococcus aureus, Salmonella sp., Proteus mirabilis, Serratia plymuthica and Pantoea agglomerans. These isolates are recorded as enteric and pathogenic in bacterial taxonomy. The results indicated that the drinking water must be safe and with high quality for human life and the presence of these enteric bacteria here are the source to contaminate drinking water by wastewater. Finally, water contamination are commonly used to evaluate the microbiological quality of drinking water and as a parameter to estimate water pollution by wastewater