Abstract
Background: Preterm PROM (PPROM), which occurs when the pregnancy is less than 37 weeks ,PROM is referred to as foetal membrane rupture occurring before to the commencement of uterine contractions (PROM).
Purpose: This study intends to evaluate the efficacy of vaginal fluid urea and creatinine for the diagnosis of preterm premature rupture of membranes and premature rupture of membranes
Patients and Methods: In the current study, 90 pregnant women between completed 28 and completed 40 weeks of gestation were included. They were divided into two equal groups: 45 pregnant women with PPROM or PROM diagnosed by pooling of fluid in the posterior fornix and 45 pregnant women attending the outpatient clinic for routine antenatal care. The posterior vaginal fornix of each group was irrigated with 5ml saline, aspirated, and then tested for urea and creatinine concentration
Results: This study demonstrated a very statistically significant difference between the groups in the vaginal fluid urea and creatinine levels between the diagnosed PPROM and PROM group compared to the control group.
Conclusion: Vaginal fluid urea and creatinine testing is a quick, easy, and non-invasive procedure that has higher sensitivity and specificity to provide an accurate diagnosis for PPROM and PROM.