Recently, nanogrease attracts considerable interest for improving the rheological properties which used in many applications such as marine applications, and water pumps. the aim of this research is to study the effect of the addition of TiO2 nanoparticles mixed with talc powder to calcium grease on properties such as viscosity, the relation between shear rate and shear stress, penetration and dropping point. For this purpose, the nanofluids were synthesized additive hybrid nanomaterials composed of 50 wt% TiO2 and 50 wt% Talc powder added in five specific ratios (0.5%, 1%, 2%, 3%, and 4%wt.). The microstructure of nanoparticles and nanogrease were examined by Transmission Electron Microscope (TEM), and X-Ray Diffraction (XRD). The experimental work was investigated by a Brookfield programmable Rheometer. The results indicated that the modified calcium grease with the concentration (3 wt. %) is the optimal concentration and the dropping point increasing about (10.6%). Moreover, the rheological behaviors of the nanogrease shows that the grease with various concentrations of TiO2 and talc powder demonstrates non-Newtonian behaviors and the results indicated that the shear stress and apparent viscosity increase with increasing volume concentration of TiO2 and talc powder to (32%) and (30%) respectively.