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Antibacterial potential of the Albizia mahalao Capuron extracts, a Fabaceae from Madagascar

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Last updated: 28 Dec 2024

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Abstract

The aim of this study was to assess the antibacterial potential of Albizia mahalao, a Madagascar Fabaceae. Leaf methanolic extracts (LME), root bark methanolic extract (RME), stem bark methanolic extract (SME), and alkaloids extracted from leaves under basic and acidic conditions were used. All the methanol extracts contained alkaloids and saponins. The antimicrobial activity was tested against many bacteria spp. including; Listeria monocytogenes, Staphylococcus aureus, Clostridium perfringens, Enterobacter aerogenes, Salmonella enterica, Shigella flexneri, and Vibrio fischeri, using the Disc diffusion and the Microdilution assays. With the exception of the SME which is inactive, the other extracts exhibited broad spectrum potential against all the tested bacteria. The alkaloids are efficient against nearly all the bacteria under both of the basic and acidic conditions, with an inhibition zone diameter (IZ) of >17 mm, and minimum inhibitory concentration (MIC) of <100 µg/ ml. RME is the least efficient (IZ ≤ 10 mm, and 100< MIC < 1000 µg/ ml). S. enterica is the most sensitive bacterium (IZ= 23 mm, and MIC= 47 µg/ ml), whereas, Staph. aureus (IZ= 10 mm, and MIC >12000 µg/ ml) is the more resistant species. The majority of the extracts expressed bactericidal potency against the tested bacterial spp. Current results revealed the antibacterial potential of the Albizia mahalao leaves and root bark extracts thus could be used to treat infectious diseases. 

DOI

10.21608/nrmj.2019.66743

Keywords

Albizia mahalao, Methanol extracts, Alkaloids, Antibacterial activity, MIC, MBC

Authors

First Name

Andriantsihoarana

Last Name

J. Razanatseheno

MiddleName

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Affiliation

Laboratory of Applied Biochemistry to Medical Sciences, Fundamental and Applied Biochemistry Department, Faculty of Sciences, University of Antananarivo, P. O. Box 906, Antananarivo 101, Madagascar

Email

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Orcid

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First Name

Lovarintsoa

Last Name

J. Randriamampianina

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry to Medical Sciences, Fundamental and Applied Biochemistry Department, Faculty of Sciences, University of Antananarivo, P. O. Box 906, Antananarivo 101, Madagascar

Email

-

City

-

Orcid

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First Name

Hanitra

Last Name

R. Randrianarivo

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry to Medical Sciences, Fundamental and Applied Biochemistry Department, Faculty of Sciences, University of Antananarivo, P. O. Box 906, Antananarivo 101, Madagascar

Email

-

City

-

Orcid

-

First Name

Danielle

Last Name

A. D. Rakoto

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry to Medical Sciences, Fundamental and Applied Biochemistry Department, Faculty of Sciences, University of Antananarivo, P. O. Box 906, Antananarivo 101, Madagascar

Email

-

City

-

Orcid

-

First Name

Victor

Last Name

L. Jeannoda

MiddleName

-

Affiliation

Laboratory of Applied Biochemistry to Medical Sciences, Fundamental and Applied Biochemistry Department, Faculty of Sciences, University of Antananarivo, P. O. Box 906, Antananarivo 101, Madagascar

Email

victor_jeannoda@yahoo.fr

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Volume

3

Article Issue

6

Related Issue

32627

Issue Date

2019-12-01

Receive Date

2019-11-16

Publish Date

2019-12-01

Page Start

502

Page End

510

Print ISSN

2537-0286

Online ISSN

2537-0294

Article File

NRMJ_Volume 3_Issue 6_Pages 502-510.pdf

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Link

https://nrmj.journals.ekb.eg/article_227696.html

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https://nrmj.journals.ekb.eg/service?article_code=227696

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227,696

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Original Article

Type Code

2,265

Publication Type

Journal

Publication Title

Novel Research in Microbiology Journal

Publication Link

https://nrmj.journals.ekb.eg/

MainTitle

Antibacterial potential of the Albizia mahalao Capuron extracts, a Fabaceae from Madagascar

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Article

Created At

23 Jan 2023