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276884

Analysis of a fractional order HIV-1 infection model with saturated immune response

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Mathematics and Computer Science

Abstract

Human immunodeficiency virus type 1 (HIV-1) infection is studied in this paper using a fractional order mathematical model. The model is made up of a set of four nonlinear differential equations that account for two forms of infection transmission (cell-to-cell and virus-to-cell) as well as a saturated immune response.The positivity and boundedness of the fractional order model solutions are studied. The values of equilibrium points and two fundamental threshold parameters
have been computed. In addition, we proved global asymptotic stability for the model equilibrium points given. To corroborate the analytical conclusions and investigate the model's dynamical behavior, numerical simulations were used. The aim of this paper is to study the dynamical behavior of a fractional order model of Human immunodefiency virus (HIV) from type 1. The proposed model consists of a system of fractional order differential equations with the consideration of two types of transmissions (cell-to-cell and virus-to-cell) with
saturated immune response

DOI

10.21608/aunj.2022.160805.1033

Keywords

HIV-1 infection, fractional-order differential equations, infectious transmission, CTL immune response, global asymptomatic stability

Authors

First Name

Shaimaa

Last Name

Azoz

MiddleName

-

Affiliation

faculty of science, dep of mathematics and computer science

Email

shaimaa.azoz@gmail.com

City

Assiut

Orcid

-

First Name

Fatma

Last Name

Hussien

MiddleName

-

Affiliation

Faculty of Science, dep os mathematics and computer science

Email

fatma_hussien11@yahoo.com

City

-

Orcid

-

First Name

Hoda

Last Name

Abdelsamea

MiddleName

-

Affiliation

faculty of science, dep of mathematics and computer science

Email

hodaabdelsamee32@aun.edu.eg

City

-

Orcid

-

Volume

52

Article Issue

1

Related Issue

38469

Issue Date

2023-01-01

Receive Date

2022-09-05

Publish Date

2023-01-01

Page Start

23

Page End

47

Print ISSN

2812-5029

Online ISSN

2812-5037

Link

https://aunj.journals.ekb.eg/article_276884.html

Detail API

https://aunj.journals.ekb.eg/service?article_code=276884

Order

276,884

Type

Novel Research Articles

Type Code

2,242

Publication Type

Journal

Publication Title

Assiut University Journal of Multidisciplinary Scientific Research

Publication Link

https://aunj.journals.ekb.eg/

MainTitle

Analysis of a fractional order HIV-1 infection model with saturated immune response

Details

Type

Article

Created At

23 Jan 2023