This study is an attempt to use the morphometric analysis of the wadi Qena watershed to predict the groundwater potential zones in the basin. The drainage network was extracted from DEM with 30 m resolution. The valley was divided into 24 sub basins, and the morphometric analysis was performed on these basins using ARCGIS 10.3 version. The stream orders range from first to sixth, and the drainage patterns are dendritic to sub dendritic in the sedimentary rocks and parallel to trellis at the basement and hard rocks. The maps of drainage density, stream frequency, elongation ratio, Constant of Channel Maintenance, drainage texture, and length of overland flow have been prepared as a layer using ARCGIS software; each layer was reclassified into 3 classes in terms of their influence on infiltration and groundwater recharge. Then these layers were combined according to their weights using a raster calculator in ARCGIS software, finally, that groundwater potential map has been produced.