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221172

Ameliorative effects of bradykinin potentiating factor, butylated hydroxy toluene and oltipraz on biochemical and histological structure of lymphoid organs in aflatoxicated femal

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Chemistry

Abstract

Aflatoxins (AFs) are chemically secondary metabolites produced by Aspergillus, Penicillium and Fusarium genera. It has adverse effects on humans and animals health due to inhibition of macromolecule synthesis. The current research investigate the pathological and biochemical changes in lymph follicles of female rats exposed to aflatoxin B1 (AFB1) for one month and the efficacy of isolated bradykinin potentiating factor (BPF) from cobra snake venom, butylated hydroxy toluene (BHT) and oltipraz (OPZ) to ameliorate those changes. Aflatoxicosis cause significant increase of lipid peroxidation (LPO) and nitric oxide (NO) in addition to significant decrease in the level of total thiols, glutathione (GSH) and the activities of glutathione peroxidase (GPx) and glutathione S-transferase (GST). Moreover, AFB1 caused
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DOI

10.21608/aunj.2020.221172

Keywords

lymph follicles, Aflatoxin B1, Oxidative Stress, butylated hydroxy toluene, bradykinin potentiating factor, oltipraz

Volume

49

Article Issue

2

Related Issue

31481

Issue Date

2020-12-01

Receive Date

2022-02-22

Publish Date

2020-12-01

Page Start

26

Page End

41

Print ISSN

2812-5029

Online ISSN

2812-5037

Link

https://aunj.journals.ekb.eg/article_221172.html

Detail API

https://aunj.journals.ekb.eg/service?article_code=221172

Order

221,172

Type

Novel Research Articles

Type Code

2,242

Publication Type

Journal

Publication Title

Assiut University Journal of Multidisciplinary Scientific Research

Publication Link

https://aunj.journals.ekb.eg/

MainTitle

Ameliorative effects of bradykinin potentiating factor, butylated hydroxy toluene and oltipraz on biochemical and histological structure of lymphoid organs in aflatoxicated female rats

Details

Type

Article

Created At

23 Jan 2023