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220881

Coordination Behavior and Biological Activity of Some Transition Metal Complexes with p-nitrophenyl and phenylazo 2, 6 diaminopyridine

Article

Last updated: 28 Dec 2024

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Subjects

-

Tags

Chemistry

Abstract

The objective of this study is to synthesize, characterize and evaluate the biological activity of p-nitrophenylazo and phenylazo 2,6-diaminopyridine and their Co(II)-, Ni(II)- and Cu(II)-chelates. The newly formed metal chelates were characterized by elemental analysis, FT-IR, mass and 1HNMR spectra, thermogravimetric analysis (TGA) and biological activity. The electronic absorption spectra and magnetic susceptibility measurements refer to an octahedral geometry structure of the prepared complexes. The antibacterial and antifungal activities of the ligands and its metal complexes were examined against bacterial species (Staphylococcus aureus, Bacillus subtilis and Escherichia coli) and fungi (Candida albicans). Ampicillin and amphotericin were used as references for antibacterial and antifungal studies. The activity data show that the metal complexes have a conscious biological activity that can be compared with the parent free ligands against bacterial and fungal species.

DOI

10.21608/aunj.2019.220881

Keywords

Azo 2, 6-diaminopyridine, transition metal complex, Antibacterial activity

Volume

48

Article Issue

1

Related Issue

31480

Issue Date

2019-06-01

Receive Date

2022-02-21

Publish Date

2019-06-01

Page Start

16

Page End

34

Print ISSN

2812-5029

Online ISSN

2812-5037

Article File

AUNJ_Volume 48_Issue 1_Pages 16-34.pdf

PDF . 545.0kB

Link

https://aunj.journals.ekb.eg/article_220881.html

Detail API

https://aunj.journals.ekb.eg/service?article_code=220881

Order

220,881

Type

Novel Research Articles

Type Code

2,242

Publication Type

Journal

Publication Title

Assiut University Journal of Multidisciplinary Scientific Research

Publication Link

https://aunj.journals.ekb.eg/

MainTitle

Coordination Behavior and Biological Activity of Some Transition Metal Complexes with p-nitrophenyl and phenylazo 2, 6 diaminopyridine

Details

Type

Article

Created At

23 Jan 2023