Posterior dislocation of lens fragments is an uncommon complication of phacoemulsification. However, it is associated with sight-threatening sequelae. These may include intraocular inflammation, secondary glaucoma, corneal edema, cystoid macular edema, and retinal detachment. Proper management is crucial to reduce the risk of these complications. Pars plana vitrectomy with intravitreal emulsification of retained lens fragments is indicated. Optimal timing for intervention is controversial. The aim of this study was to determine clinical outcomes of prompt, early and late pars plana vitrectomy for dislocated lens fragments and / or IOL. Thirty-five eyes were included and divided into three subgroups according to the timing of PPV (prompt, early and late). All eyes underwent 23-gauge PPV. The results illustrated that 22.2 % of prompt PPV achieve good visual outcome compared to only 8.3% and 7.14 % in early and late subgroups respectively. More than one third of cases (35.7 %) in late PPV ended with poor visual outcome. We concluded that timing of PPV is an important factor affecting clinical outcomes in cases complicated with dislocated nuclear fragments and/or IOL. The prompt PPV was associated with the best outcome followed by the early PPV. Delayed PPV had the worst prognosis.