272564

Inflammatory changes in Covid19 patients and role of tocilizumab

Article

Last updated: 05 Jan 2025

Subjects

-

Tags

Healthcare research

Abstract

COVID-19 is a fast-growing worldwide danger that the WHO has classified as a pandemic. COVID-19 infects the patient's respiratory tract and causes pneumonia in the majority of patients. It can also cause acute respiratory distress or ARDS in roughly 15 percent of Covid-19 cases. The existence of the virus's so-called "cytokine storm" Covid-19 infection was therefore linked to death in patients.. Increased proinflammatory cytokine production exacerbates ARDS and causes significant tissue damage. Due to that fact, there is also the chance that It can cause multi-organ organ failure in certain circumstances. Using cytokines as a target during COVID-19 treatment might help patients live longer and die less. Due to the fact that IL-6 is one of the likely reported cytokines to be enhanced in people who are suffering from Covid-19. Also, it is proven that elevated IL-6 can be directly linked to higher levels of death, tocilizumab is the ideal solution as a therapy for a cytokine storm that can come with Covid-19.
 
 

DOI

10.21608/mjmr.2022.272564

Keywords

COVID-19, Tocilizumab, Inflammatory changes

Authors

First Name

Heba

Last Name

Ebrahim

MiddleName

A.

Affiliation

Department of Chest Diseases, Faculty of Medicine, Minia university

Email

heba5050ashraf@gmail.com

City

-

Orcid

-

First Name

Nezar

Last Name

Tawfik

MiddleName

R.

Affiliation

Department of Chest Diseases, Faculty of Medicine, Minia university

Email

nezarrifaat@yahoo.com

City

-

Orcid

-

First Name

Rasha

Last Name

Abdelfattah

MiddleName

A.

Affiliation

Department of Chest Diseases, Faculty of Medicine, Minia university

Email

rashachest2010@yahoo.com

City

-

Orcid

0000-0003-3884-7402

Volume

33

Article Issue

3

Related Issue

36205

Issue Date

2022-07-01

Receive Date

2022-06-09

Publish Date

2022-09-01

Page Start

65

Page End

69

Online ISSN

2682-4558

Link

https://mjmr.journals.ekb.eg/article_272564.html

Detail API

https://mjmr.journals.ekb.eg/service?article_code=272564

Order

272,564

Type

Review Article

Type Code

2,215

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Inflammatory changes in Covid19 patients and role of tocilizumab

Details

Type

Article

Created At

23 Jan 2023