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259081

Risk factors analysis for mortality among a cohort of lung cancer patients

Article

Last updated: 28 Dec 2024

Subjects

-

Tags

Healthcare research

Abstract

Background: Over the last few decades, the worldwide burden of cancer has been increased. More than half of the 18.1 million people diagnosed with cancer in 2018 died. Lung cancer diagnoses and deaths are on the rise. So that it is very important to investigate the factors that influence lung cancer mortality. The aim is to assess the characteristics of lung cancer patients and the factors influencing mortality due to lung cancer. Methods: A cross-sectional observational study was performed on 58 lung cancer patients (48 with Non-Small Cell Lung cancer(NSCLC) and 10 with Small Cell Lung Cancer(SCLC) with a mean age 58.9 yrs. Forty-nine of them were males, one third were current smokers and 56% of them had advanced stage of lung cancer (stage III and IV). Survival was calculated from the date of enrollment in the study to the date of the last follow-up visit (3 years) or death. Results: Seventy-five of the studied patients died with an average survival duration of 19 months for NSCLC patients in comparison to 12 months for SCLC patients. Patients > 60 yrs., those with SCLC, current smokers and those with performance status ≥ 2 had a low survival time. Univariate regression analysis identified that advanced stage of cancer had a 6-fold increase in mortality (p=0.0001). Conclusion: Age more than 60, performance status ≥ 2 and stage III and IV were found as significant independent factors linked with raised mortality rate.

DOI

10.21608/mjmr.2022.132713.1076

Keywords

Non- Small Cell Lung Cancer, small cell lung cancer, survival time, mortality rate

Authors

First Name

Hager

Last Name

Mohamed

MiddleName

Yehia

Affiliation

Chest department, faculty of medicine, minia university hospital, minia, minia

Email

yehiahager86@yahoo.com

City

-

Orcid

-

First Name

azza

Last Name

said

MiddleName

farag

Affiliation

Faculty of Medicine, Pulmonary Medicine Department, Minia University, Minia,

Email

azza20022@yahoo.com

City

minia ,egypt

Orcid

-

First Name

amel

Last Name

kamal

MiddleName

mahmoud

Affiliation

Faculty of Medicine, Clinical Pathology Department, Minia University, Minia,

Email

amlkoktail@yahoo.com

City

minia ,egypt

Orcid

-

First Name

shady

Last Name

anis

MiddleName

elia

Affiliation

Faculty of Medicine, Pathology Department, Cairo University, Cairo, Egypt

Email

shadyeliaanis76@yahoo.com

City

cairo, egypt

Orcid

-

First Name

Zainab

Last Name

Saeed

MiddleName

Hassan

Affiliation

Chest department, faculty of medicine, minia University, minia, Egypt

Email

chestawya@yahoo.com

City

El minia

Orcid

-

Volume

33

Article Issue

3

Related Issue

36205

Issue Date

2022-07-01

Receive Date

2022-04-23

Publish Date

2022-07-01

Page Start

19

Page End

29

Online ISSN

2682-4558

Link

https://mjmr.journals.ekb.eg/article_259081.html

Detail API

https://mjmr.journals.ekb.eg/service?article_code=259081

Order

259,081

Type

Original Article

Type Code

2,212

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Risk factors analysis for mortality among a cohort of lung cancer patients

Details

Type

Article

Created At

23 Jan 2023