Introduction: The skin is the largest organ of the body that serves multiple functions essential to the 
survival of the body, which may be compromised by the presence of burn, including thermal 
regulation, prevention of fluid loss by evaporation, hermetic barrier against infection and Sensory 
receptors that provide information about the environment. Aim of the work: The aim of this 
prospective study was to evaluate the effect of platelet rich plasma application on different types post 
burn scars. The hypothesis of the study is the previous options of the treatment of burn scars are 
satisfactory, if we can prove that platelet rich plasma, with using micro needling treatment therapy 
add an advantage in this field, it will be addition to the previous treatments. This study was conducted 
to answer the following questions: If PRP effective in treatment of post burn scars?, Can PRP applied 
to all types of post burn scars?, Is there are any complications?. Patients and Methods: This 
prospective clinical study was performed at the Plastic surgery department, Minia University Hospital 
in the period from February 2016 to July 2017, patients were counseled and signed informed consents, 
skin punch biopsies and photographs were obtained from all participants in this study. Results: 1. 
Demographic Data of the Patients: Twenty patients were enrolled in this study, the twenty patients 
completed the whole treatment and follow up protocol. Twenty patients, including eighteen females 
(90%) and two males (10%). Their ages ranged between 5 and 35 years (mean 16.7±10.8). All 
patients skin photo types were II-IV. Discussion: Burn scars represent a major challenge. In addition 
to significant morbidity to the scars themselves, side effects and lengthy courses of many therapeutic 
modalities represents an additional burden to the patients (Brusselaers et al., 2010). 
Recommendations: Further controlled studies with larger number of patients regarding the number of 
sessions and interval between sessions are recommended to estbestablish efficacy of platelet rich 
plasma therapy for the treatment of post burn scars.