Beta
ManageSearchChatDiscover
223012

Resistance to anti-angiogenic therapy in patients with neovascular age-related macular degeneration

Article

Last updated: 28 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Healthcare research

Abstract

Age-related macular degeneration (AMD) is the most common cause of irreversible vision loss in 
developed countries among individuals aged 50 years and older. The neovascular form of late AMD 
affects only 10% of patients but is responsible for most cases of severe vision loss due to the disease. 
Despite their good results in treatment of neovascular AMD, anti-angiogenic agents can be ineffective 
in a subset of patients considered resistant to therapy. Several mechanisms have been proposed to 
explain his phenomenon and, subsequently, different management strategies are currently under 
investigation to improve patient outcomes with anti-angiogenic therapy.

DOI

10.21608/mjmr.2022.223012

Keywords

anti-angiogenic, neovascular, macular degeneration

Authors

First Name

Mohamed

Last Name

Hamid

MiddleName

A.

Affiliation

Department of Ophthalmology, Minia University Hospital, Minia, Egypt

Email

-

City

-

Orcid

-

First Name

Sahar

Last Name

Abdelaziz

MiddleName

TA.

Affiliation

Department of Ophthalmology, Minia University Hospital, Minia, Egypt

Email

-

City

-

Orcid

-

First Name

Ahmed

Last Name

Sabry

MiddleName

M.

Affiliation

Department of Ophthalmology, Minia University Hospital, Minia, Egypt

Email

-

City

-

Orcid

-

First Name

Khaled

Last Name

Mourad

MiddleName

M.

Affiliation

Department of Ophthalmology, Minia University Hospital, Minia, Egypt

Email

-

City

-

Orcid

-

First Name

Azza

Last Name

Shehab

MiddleName

A.

Affiliation

Department of Ophthalmology, Minia University Hospital, Minia, Egypt

Email

-

City

-

Orcid

-

Volume

30

Article Issue

1

Related Issue

31958

Issue Date

2019-03-01

Receive Date

2022-03-05

Publish Date

2019-03-01

Page Start

212

Page End

216

Online ISSN

2682-4558

Article File

MJMR_Volume 30_Issue 1_Pages 212-216.pdf

PDF . 109.1kB

Link

https://mjmr.journals.ekb.eg/article_223012.html

Detail API

https://mjmr.journals.ekb.eg/service?article_code=223012

Order

223,012

Type

Original Article

Type Code

2,212

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Resistance to anti-angiogenic therapy in patients with neovascular age-related macular degeneration

Details

Type

Article

Created At

23 Jan 2023