Background: Varicocele is considered a major cause of male infertility with a prevalence 
rate of about 15% in healthy men and 40% in men being treated in infertility clinics. Semen 
analysis remains the single most useful and basic investigation for diagnosing male infertility.
Objectives: The aim of the present study is to define effect of varicocele on semen 
parameters. Methods: The study was conducted on 80 males with age ranging from 20 to 50 
years. Semen analysis was done in all patients. They were divided into two groups: Group I 
(control): 25 fertile persons with no varicocele. Group II: patients with varicocele. Results:
There was a statistically significant increase of mean total sperm count, total sperm motility 
(%), progressive motility (%) and normal morphology (%) of control group in comparison to 
group II. Conclusion: varicocele causes alternation of spermatogenesis with subsequent 
decrease of seminal parameter (count, motility, normal morphology).