Background: The history of substance use is as old as society itself; it has recently become a global issue affected by social, economic, political, and psychosocial variables. The problem is not only that of a person or a group, and a drug, but it includes the triad's interaction. The multiplicity and interrelationship of variables associated with substance addiction makes the topic a complicated one. Objective: To describe sociodemographic characteristics in a sample of patients diagnosed with Substance Use Disorders. Methods: subjects of the study were selected from clients attending addiction "Hotline" clinic of Minia Hospital for Mental Health and Addiction Treatment. Only the first, middle and last clients attending the Hotline clinic were included to ensure random selection, along with all the inpatients who have spent at least 7 days stay in the detoxification department. The Mini Neuropsychiatric International Interview (MINI)Plus measured the DSM-IV diagnostic criteria for drug use disorders. Results: The mean age of the studied sample was 30.1±6.7 years ranging from 18 to 56 years, most of the sample were males 96.6%, more than half of the sample were married 57.1% and the rest were mostly single 35.3%, the most common educational level was technical secondary school 37% followed by illiteracy 26.1%, most of the sample were manual workers 62.2% followed by being not working 15.1%, and finally the residence in the studied sample was almost equally divided between being from rural areas 54.6% and urban areas 45.4%. Conclusion: substance use is more common in third decade of life, more common in males more than females.