Introduction: Throughout the entire female reproductive lifespan, the ovary relies on the reserve of 
resting follicles or ‘ovarian reserve' which is a measure of ovarian ageing. It is defined by the 
quantity and quality of the remaining primordial follicular pool within the paired ovaries at any given 
time. Aim of the Work: The aim of our study is to compare 2D ultrasound imaging with 3D 
ultrasound imaging for assessment of ovarian function in infertile female. Patients and Methods: 
This Observational prospective study was done in the department of Obstetrics and Gynecology 
Minia maternity university hospital in the period of February 2018 to July 2018. This study was 
approved by the local ethical committee of research department of Obstetrics & Gynecology, Minia 
University. Results: The collected data used for comparison between use of two dimension and 
three dimension ultrasound for evaluation of ovaries of infertile patients - including patient's 
characteristics, fertility data and 2D & 3D measurements - were tabulated and shown infigures.
Conclusions and Recommendations: Three-dimensional ultrasonography is an imaging modality 
that can be used as a complementary method for other endocrine markers for the assessment of 
ovarian reserve. It allows excellent evaluation of the ovaries with direct quantitative estimation of 
antral follicle count, ovarian volume and with power Doppler. Using 3D software including 
sonoAVC™ and VOCAL™ programs can increase accuracy and efficacy of ovarian evaluation.
Patient examination with 3D ultrasound is less time consuming and less patient discomfort.