Introduction: Trauma is the most common cause of death in all over the world. The most frequent 
mechanisms include motor vehicle collisions and pedestrian injuries. Aim of the work: The aim of 
this study is to evaluate the effect of biological and hematological makers in prognosis of outcome of 
adult trauma patient admitted to ICU in Minia University Hospital. Patients and Methods: After 
obtaining an approval from our hospital – El-Minia university hospital – ethics committee and 
obtaining written consent from the patient or responsible relative, in a period of six months, adult 
trauma patients will be approached and enrolled in the study. Results: The rate of adult trauma 
admissions was 42.34% of the total ICU admissions which was 307 cases; there were 106(81.53%) 
males and 24 (18.46 %) females with a male to female ratio of 4.41:1. Conclusion: We concluded that 
trauma constitutes a significant cause of admissions into the general ICU and a very high incidence of 
morbidities and mortality including increased hospital course complication.