Introduction: Chronic kidney disease (CKD) refers to a condition related to irreversible kidney 
damage that can further progress to end- stage renal disease (ESRD).CKD is an increasing problem 
worldwide and is now being recognized as a global health burden particularly for cardiovascular and 
cerebrovascular ischemic events. Neurological manifestations related to electrolyte disorders, drug 
toxicity, and uremia are common in CKD. Aim of the Work: The aim of this study is to: Detect 
electroencephalogram (EEG) findings in different stages of chronic kidney disease for better 
evaluation and management of uremic encephalopathy. Subjects and Methods: This is a prospective 
observational study included 54 children with different stages of chronic renal diseases (from stage 1 
to stage 5, undialysed and haemodialysed). All patients were recruited from the pediatric nephrology 
unit and pediatric hemodialysis unit at El-Minia university hospital, Minia governorate during the 
period from March 2015 to October 2016. Results: This is study included 54 children with different 
stages of chronic renal diseases (from stage 1 to stage 5). Recommendation: We recommend that 
EEG can be used to detect latent or subclinical encephalopathy, it will be helpful as a prognostic 
indicator of response to clinical therapy of CKD. One of our study limitations is the small number of 
studied cases, but our preliminary results could be the base for further evaluation. So, further studies 
with larger sample size is recommended for evaluating Electroencephalogram findings in different 
stages of chronic kidney disease.