Introduction: In the broad sense, voice refers to the sound we produce to communicate 
meaning, ideas, opinions, etc. In the narrow sense, voice, as in this review, refers to sounds 
produced by vocal fold vibration. Aim of the work: The aim of this work is to determine and 
analyze voice problems in patients with renal failure to establish a base line data about the 
size and distribution of the propable voice disorder in these patients in order to facilitate early 
detection and proper management of these voice problems. Subjects and Methods: This 
study included 110 individuals, age ranging from 25 years to 70 years. Results: I. 
Descriptive and comparative analysis: The individuals in this study included in two 
groups: The study group (GI): patients suffering from chronic renal failure (n=54). They 
were 38males(70.3%) and 16 females (29.6%),with a mean age of46.66 ± 12.65 and a range 
of 25 years to 70years. The control group (GII): This group included 56 individuals not 
suffering from renal failure. They were 40 males (71.4%) and 16 females (29.5%), with a 
mean age45.55 ± 11.05 and a range of 25 years 70 years. Conclusion & Recommendation: 
The results of our study revealed that subjects with chronic failure exhibit a clinical evidence 
of voice disorders and proving that there is interplay of different body systems and the larynx.