Malnutrition is a major issue in patients with chronic kidney disease (CKD), adversely affecting 
morbidity, mortality, functional activity and patients' quality of life. Our knowledge of the pathogenic 
mechanisms of malnutrition in patients with CKD, including endstage renal disease, has been 
improved. This has led to the development of clinical practice guidelines for nutritional care in CKD 
which provide a framework for the nutritional issues facing patients and physiccians. Extensive 
research in the field of nutrition in patients with CKD has resulted in the formation of general 
guidelines, although some uncertainties still exist on some of the best therapeutic or preventive 
options in uremic malnutrition. It is important to search actively for malnutrition since early diagnosis 
and treatment can improve the prognosis for CKD patients and reduce the monetary costs connected 
with treatment.