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221716

Efficacy of thyroid isthmusectomy and its outcomes in patients with single isthmic papillary thyroid carcinoma: a single-center observational study

Article

Last updated: 05 Jan 2025

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Healthcare research

Abstract

Background; Despite the total thyroidectomy is recommended for isthmic papillary thyroid 
carcinoma (PTC), the gold standard surgery is not well-known. We aimed to investigate the 
efficacy of isthmusectomy and its outcomes in the treatment of isthmic PTC. Methods; All
patients with single isthmic PTC and underwent total thyroidectomy with or without central 
neck dissection (CND) were included in the study. Patients with cervical lymph node 
metastasis and neck extension or patients with their cancer in another place were omitted 
from the study. Included patients were subdivide into 3 groups; total thyroidectomy, 
lobectomy with isthmusectomy, and isthmusectomy. Clinical and pathologic data and surgical 
outcomes were collected. Results: Among the included 121 patients, 28 were males and 93 
were females. Total thyroidectomy, isthmusectomy, and lobectomy with isthmusectomy were 
conducted in 70 (57.8%), 11 (9.1%), and 40 (33.1%), patients, respectively. Patients with total 
thyroidectomy showed increased postoperative hypoparathyroidism than patients with 
lobectomy and isthmusectomy. On the other hand, there were no significant differences in the 
recurrence rate or the survival between the 3 groups. Conclusion; Total thyroid
isthmusectomy may be helpful in the surgical management of small single isthmic PTC. 
Further studies are needed to verify this result.

DOI

10.21608/mjmr.2022.221716

Keywords

Isthmusectomy, Papillary thyroid carcinoma

Authors

First Name

Ahmed

Last Name

Mohamed

MiddleName

Elsayed

Affiliation

Department of Surgical Oncology, Faculty of Medicine, Al-Azhar University, Cairo Egypt.

Email

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City

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Orcid

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First Name

Alsayed

Last Name

Moghazy

MiddleName

Basiony

Affiliation

Department of General Surgery, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Email

-

City

-

Orcid

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Volume

30

Article Issue

4

Related Issue

31649

Issue Date

2019-10-01

Receive Date

2022-02-24

Publish Date

2019-10-01

Page Start

198

Page End

205

Online ISSN

2682-4558

Link

https://mjmr.journals.ekb.eg/article_221716.html

Detail API

https://mjmr.journals.ekb.eg/service?article_code=221716

Order

33

Type

Original Article

Type Code

2,212

Publication Type

Journal

Publication Title

Minia Journal of Medical Research

Publication Link

https://mjmr.journals.ekb.eg/

MainTitle

Efficacy of thyroid isthmusectomy and its outcomes in patients with single isthmic papillary thyroid carcinoma: a single-center observational study

Details

Type

Article

Created At

23 Jan 2023