Introduction :Elastography is a new imaging modality that maps the elastic properties of soft 
tissue(1)
. The main idea is that whether the tissue is hard or soft will reflect a diagnostic 
information about the presence or status of disease. For example, tumors will often be harder 
than the surrounding tissue.(2)
. Elasticity is the tendency of a tissue to resume the original size 
and shape; while strain is the level of change in size or shape in response to external 
compression (stress)(3) Aim of the work: The aim of this study is to assess the role of 
Ultrasoud Elastography in evaluation of thyroid nodules. Anatomy of the thyroid gland: 
The thyroid gland is placed anterior in the lower neck at the level of 5th cervical to 1st
thoracic vertebrae. It consists of 2 lateral lobes interconnected in front of the second, third and 
fourth tracheal rings by narrow median isthmus(19)
. Patients and methods: The objective of 
this study is to assess the diagnostic accuracy of US elastography in evaluation of thyroid 
nodules using the cytological & histopathologic analysis as the reference standard.