Objectives: to assess the left atrial deformation parameters in patients with moderate to severe mitral 
stenosis by transthoracic echocardiography. Methodology: this study was conducted on 30 patients 
with moderate to severe mitral stenosis presented to Cardiovascular Department in Minia University 
Hospital from 1/11/2018 to 30/10/2019, Left atrial (LA) volume parameters (maximum, minimum 
and pre atrial contraction) were measured. Results: 25 patients (83.5%) in this study had increased 
maximal left atrial volume (>34 ml indexed to body surface area) and 5 patients (16.7%) had normal 
maximal volume (<34ml/BSA) with median LA MAX volume (61.5 ml/BSA) and for minimal left 
atrial volume 26 patients (86.7%) had increased minimal left atrial volume (>14 ml/BSA) and 4 
patients (13.3%) had normal minimal LA volume (<14 ml/BSA). Conclusion: left atrial deformation 
parameters were impaired in patients with moderate to severe mitral stenosis detected by transthoracic 
echocardiography.