Introduction: The World Health Organization (WHO) recently reported that depression is a major cause of disability worldwide, with more than 320 million people affected globally (World Health Organization, 2017). Aim of the work: is to describe sociodemographic characteristics in a sample of patients diagnosed with major depressive disorder. Patients and
methods: 51 Patients were referred from the outpatient psychiatric clinics of Minia governorate, Minia University hospitals outpatient psychiatric clinic, Minia psychiatric hospital and the study was held in Minia university hospitals during the period from December 1, 2018 to October 1, 2019. Results: the mean age of the sample was 35.44 ± 
10.402 years, ranging from 18 to 55 years. Nearly half of the participants were females (55.6%). More than a half of them (57.8%) were married, while (31.3%) were single. Rural residents (53.3%) were more common than urban (46.7 %). The most common educational level was high-education (31.1%) followed by technical education (26.7%). Full time mployees were (53.3%) followed by unemployed and not looking for work (31.1%). The majority of patients (73.3%) reported significant environmental stressor or precipitant prior to the onset of depression. Conclusion: depression is more common in third decade of life, more common in females more than males and highly-related to significant life stressors.