Introduction: Sepsis is a life threatening condition which affects many children, Sepsis is said to be 
one of the leading causes of death among children even in advanced countries. Aim of the work: to
verify the association between cardiac dysfunction and serum ferritin level with unfavorable outcomes 
in pediatric sepsis. Patients and Methods: This prospective cohort study was carried out on 40 
patients with suspected or confirmed sepsis in our PICU. All patients in the study were subjected for 
assay of serum levels of ferritin, CRP and echocardiography on Day of admission & Day 3. Results: 
Serum Ferritin level was significantly higher among cases with cardiac dysfunction than cases without 
cardiac dysfunction. There was highly statistically significant difference between day of admission D1 
and third day as regard to serum ferritin level and CRP with median value of Ferritin level and CRP 
were higher on the day of admission compared to third day.