Abstract
The purpose of this study evaluated the Percentage of association between cranial congenital fetal 
anomalies and extra-cranial congenital fetal anomalies. Patients and methods: The study conducted 
for two years in Minia University Fetomaternal Unit 2018-2019, We examined 2091 cases referred to 
us from all Minia regions because of congenital anomalies risk ,263 cases detected carrying different 
types and numbers of anomalies . Results: The number of congenital anomalies in this study was 263 
with percentage (12.5%) but when these number of congenital anomalies linked to all Antenatal care 
cases that attached to Minia University hospital in two years with average number (40,000) cases in
two years we found percentage was (0.65%).In this study the top affected system was the central 
nervous system with percentage 32.7% ,then the renal system 18.6%, then the cardiovascular system 
14.8% ,then the chest 8%, then the musculoskeletal system 7.2% then hydrops fetalis 6.5% followed 
by GIT 5.7% then the neck 5.3%, followed by face which was the least prevalent Anomalies which 
the percentage was1.1%. Conclusions: We found that CNS was the most common system affected 
and the most rare system affected was the face. The ratio of congenital anomalies in Minia 
Governorate was 0.65% Which was less than the global percentage.