Aim of the study: Even though laparoscopic hepatectomy (LH) has proved to be both safe and 
effective in specialized centers; the restricted indications for resection in the case of benign liver 
lesions has resulted in poorly reported outcomes. Our aim was to describe the short and long-term 
results of LH to treat benign hepatic lesions, including quality of life (QoL) evaluation. Patients and 
Methods: Thirty-one LHs were performed between 2016 and 2018 in 30 patients. We evaluated QoL 
with the SF-36 test and a body image satisfaction questionnaire by personal interview before surgical 
treatment and at 1 month, 3 months, 6 months and 1 year after surgery. Results: Median age was 38 
years (range 21-71) and the majority were females (68%). The most frequent etiology was hepatic 
adenoma in 16 patients (52%), followed by focal nodular hyperplasia (n = 4), cavernous hemangioma 
(n = 3), hepatic abscess (n = 3), cystadenoma (n = 5) and hepatolithiasis (n = 1). The majority of 
resections were minor (66%) and the conversion rate was 6.2%. Pathological examination confirmed 
negative margins in all patients. Postoperative mortality was nil, while morbidity was 6.2%. Median 
hospital stay was 4 days (range 1-32 days). In a median follow-up of 48 months (range 2-120), 2 
patients experienced recurrence. QoL variables were similar between the preoperative and 
postoperative periods. Conclusion: LH should be considered the main therapeutic approach for 
treating selected patients with benign liver lesions who require surgical resection because it presented 
both null mortality and low morbidity, along with rare recurrence, a good quality of life and high 
esthetic satisfaction.