: Postoperative early subjective cognition has been reported after cardiac and non-cardiac 
surgery. The method of surgery and anesthetic are believed to be associated with the incidence, but 
there are few prospective evidence comparing the incidence after various procedures and on long 
term3
. Patients and Methods: A total of 60 adult patients of both sex, ASA I-ІІI aged between 40 to 
60 years, scheduled for surgery under general anesthesia were included in the study. Patients were 
randomly allocated into 2 equal groups each containing 30 patient. Group (B) surgery group and 
group (C) control group of the patients' relatives. Results: There was no significant decrease in 
instrumental activity of daily living (IADL) and subjective cognitive function questionnaire after 3 
months between the two groups. Conclusion: we concluded that general anesthesia can cause early 
postoperative and no significant effect on delayed subjective cognition after major non cardiac 
surgeries.