Colorectal cancer is one of the most common health threatening diseases 
around the globe as it is the third most frequent cancer worldwide and surgical resection is the 
mainstay of potentially curative treatment, Using of laparoscopy in colon surgery quickly 
diffuse in surgical practice since its introduction in the 1990's from an experimental
infrequently performed approach to the current standard of care, as only few studies, 
nonrandomized and including small populations, have compared LCS to OCS, with no clear 
advantage of one approach over the other. Aim of the study: To compare efficacy between 
laparoscopic and open colectomy in patients with colonic carcinoma. Subjects and methods:
A total of 134 patients attending Helwan and Zagazig University hospitals from January 2018
to January 2021 included in a prospective study. Participants were divided into two groups 
according to type of surgery.Group 1: included "66 patients" comprised those who had 
colonic with laparoscopic intervention. Group 2: included "68 patients" comprised those who 
had colonic carcinoma with open surgical intervention. Results: In LCS group, 54 patients 
had no post-operative complications while in OCS group, 36 patients had post-operative
complications in the form of leakage, intra-abdominal infection, chest infection, wound 
infection & burst abdomen (P=0.000). There was a statistical significant difference between 
study groups in postoperative complications as only 12 patients of laparoscopic colectomy 
patients had postoperative complications. Conclusion: Laparoscopic colectomy is safe, valid 
and considered an effective surgical method for resection of colonic carcinoma.
Recommendation: We recommend laparoscopic resection as a gold standard for patients 
with colonic carcinoma.