Introduction: Bladder cancer is one of the most common malignancies occurring worldwide. Bladder 
cancer develops predominantly in males with a ratio male: female (3:1). In developed countries, 
Urothelial cell carcinoma (UCC) is the predominant bladder tumor (>90%) of cases. In Egypt, 
previous research has reported a significant decrease in squamous cell carcinoma (SCC) over the past 
30 years but the overall bladder cancer incidence is steady due to increase in UCC and this has been 
explained due to decrease in S.haematobium (SH) with increase in smoking. Aim of the work: 
Through a study that will be conducted at Urology and Nephrology Minia university hospital we will 
report the patterns (clinically, radiologically, and histo-pathologically) of bladder cancer patients 
presented to our institution in the period between 2020-2021. Patients and Methods: Our study is a 
prospective clinical study conducted on 120 patients who attended to our outpatient clinic at 
Nephrology and Urology Minia University Hospital in the period from February 2020 to March 2021. 
We included all patients presented to our institution with bladder mass, while patients who received 
chemotherapy or radiotherapy, or did Previous cystoscopic resection with intravesical therapy; were 
excluded from our study. Results: This study was conducted on 120 with bladder cancer. Male: 
female ratio was 5:1 with median age of 59.73 years. About 80 cases were from rural area. The main 
presenting symptom was gross hematuria with clots in about 72% of cases. During this study, 
sensitivity of urine cytology was 32.5 % and noticed that it increased mainly with high grade tumors. 
We did complete TURBT in 50 cases for masses with size lower than 3 cm and histopathology of all 
resected tumors showed that, about 78 cases were UCC, 36 were SCC and 6 were ADC. About 
62.5%of cases were high grade tumors. During this study, we assessed correlation between urine 
cytology and tumor grading and the relation was statistically significant but on the other hand, the 
relation between cytology and tumor staging was statistically insignificant.