The global warning released by Boris Johnson during the United Nations climate conference 2021 sounded the alarm about the environmental danger posed to the city of Alexandria- Egypt. Alexandria is an inherited valuable legacy as one of the oldest cities in known history; since its origin, Mariout lake represents the ecological key factor in raising its urban formation. This study targeted to highlight the influential role of Mariout lake in regenerating Alexandria city ecologically; it argued that the keystone for this process is a dual urban regeneration process for both regions based on the dual impact of ecological issues between the lake and city regions across history. This approach follows a sophisticated process to analyze the inherited social and economic urban formation for the lake's range as a key to rehabilitating the ecological issues for the Alexandria City region. the outcomes recommended an urban scenario for a sustainable redevelopment process for the city and the lake. Optimally, the paper seeks to present an academic approach to developing an urban regeneration process based on the origin of the urban environment for the lake range and the city region.