Recently, many countries, including Egypt, sought to establish new sustainable cities, in addition to improving the outdoor spaces in the existing cities to achieve the criterion of sustainable cities. This is in contrast to the high energy consumption in residential buildings because of raising in comfort requirements and living standards. Hence, there is a need to investigate the influence of passive strategies on outdoor and indoor thermal comfort in the present time and predict their efficiency for facing the upcoming climate change in the two future periods 2050 and 2080. Consequently, this study proposes a coupled-simulation methodology to study the impact of a set of outdoor and building passive strategies, within 2 stages; a) simulation of outdoor thermal comfort by Envi-met software and b) simulation of indoor thermal by using DesignBuilder in 2020, 2050 and 2080. The main aim of this study is improving outdoor and indoor thermal of residential buildings and energy consumption rationalization in a new desert city in Egypt. The results concluded a significant reduction of air temperature (Ta) and Physiological Equivalent Temperature (PET) by 4.95°C and 15.1°C, respectively while applying a hybrid solution of semi-shading 50% and trees. Furthermore, a remarkable reduction in energy consumption by integrating green façades and roofs with the LED lighting system reached 32.67%. the study provides a helpful methodology for designers and planners to predict current or future indoor and outdoor thermal comfort to adapt to climate changes.