The objective of this study was to assess the physicochemical parameters of effluents from sewage treatment plant effluents: A case study from Sohage Governorate, Egypt. Additionally, the levels of heavy metals were evaluated. The quality of effluent from the sewage treatment plant was assessed to determine the effect that may have appeared on environmental pollution. Effluents were sampled before treatment and after treatment were collected and analyzed for pH, total dissolved solids (TDS), biochemical oxygen demand (BOD), dissolved oxygen (DO), nitrates, phosphate, oil and grease. After treatment, the average values were 7.4 and 8.08 for pH, 523 and 484 for TDS, 45 for NO₃, 8 and 9 for NO₂, 171 and 24.1 for BOD, 227 and 72.5 for COD, 22 and 5.5 for oil and grease, 5.4 and 9.2 for TKN, and 2.8 and 0.19 for PO₄, 3.9 and 0.22 for H2S, and 0.5 and 4.28 at west Sohag and El-Cola treatment plant, respectively. Most of these parameters, including BOD, COD, TKN, PO₄, H2S and oil and grease at west Sohag sewage treatment plant, DO at El-Cola, NO₂ and NO₃ at two treatment plants, were above the Egyptian standards. However, the results indicate that the estimated concentration of heavy metals (Al, Cu, Fe, Li, Mn, Ni, Pb, Se, Cd, Zn, Cr, Hg, V, Co, Br, Mo) in waste disposal (final seepage) are generally low at the two treatment plants and they do not exceed the permissible limits for the Egyptian code. It could be concluded that caution must be taken during the discharge of poor-quality effluent (especially from west Sohag treatment plant) into the environment.