Field experiments were conducted at a private farm located at Abu Qurqas, El-Minia, Egypt, during the 2018/2019 and 2019/2020 seasons. The aim of this research was to assess the impact of the effect of fertilization systems and weed control treatments, on yield and quality of sugar beet as well as associated weeds. A randomized complete block design (RCBD) was used, in a split plot arrangement and replicated three times. The main-plots were devoted for fertilization systems, while the weed control treatments were randomly located in the sub plots, in both seasons. Results confirmed that, fertilization systems exhibited a significant effect on most studied traits in both seasons, except TDW (g/m²) in both seasons; RSY (ton/ fed); SR%; LS% and QZ% in the first season. Weed control treatment had a high significant effect on all studied characteristics except α - amino-N% in both seasons, K% in 1^st, Na% and SR% in 2^nd one, all weed control treatments, except un-weeded, decreased dry weight of total - leaved weeds, b₂ and b₃ out-yielded other weed control treatments for root, sugar yields and quality.
Generally, it could be summarized that fertilization sugar beet by50% from recommended chemical nitrogen + red yeast with Tegro 27.4% or Safari 50 % WG  12 g/fed. to maximize the productivity and quality of sugar beet yield.