Biological control of root-knot nematodes using organic amendments such as compost and Trichoderma has been recommended as an alternative effective strategy in disease management and stimulating the chemical and physiological aspects of tomato plants. In this experiment, four types of compost at three doses were evaluated for their efficacy in the root-knot nematode (Meloidogyne javanica) control and physiological traits of tomato plants under greenhouse conditions. Results showed that amending the soil of the pot with the compost markedly reduced the root-knot nematode related parameters in tomato plants. The root galling, egg masses and females were decreased in the treated plants compared with infected non-treated control plants. Mixed type at 3% had a phytotoxicity effect in tomato plants. Supplemented the soils with the compost also inhibited the population of second-stage juveniles (J2s) in the soil. All compost type (Animal, plant, Trichoderma Biofortified, and mixed) increased significantly plant height, leaf area fresh and dry weight, photosynthetic pigments, total and soluble carbohydrates, proline and phenol concentrations as well as and water balance occurred in tissues of tomato plants. Meanwhile, the third level of all organic fertilizers caused a significant decrease in all growth characteristics of tomato plants. Thus, the current study results confirmed that compost could offer a satisfactory sustainable ecofriendly tactic for root-knot nematodes management and soil fertility improvement.