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253039

Effect of Some Plant leaves extract on diabetic rats

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Last updated: 23 Jan 2023

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Abstract

Searching for effective, low cost and less side effect containing herbal hypoglycemic agents is important therefore, the present study was performed to evaluate the effect of olive leaves and stevia leaves of alcoholic extracts on diabetic rats. A total of thirty six male healthy rats, weighing (201±1.5g) were classified in to 2 main groups of extraction of olive leaves and stevia leaves each group was classified into 2 subgroup (levels of each type of extract at 0.2 and 0.5 %); in addition to the control negative (-ve) and the control positive (+ve) groups. The rats were divided into six groups: Group (1), the control negative (-ve) was fed on the basal diet. Group (2), the control positive (+ve) (diabetic rats) was fed on the basal diet. Groups (3 and 4) are diabetic rats fed on the basal diet containing olive leaves extract at 0.2 and 0.5 % respectively. Groups (5 and 6) are diabetic rats groups fed on the basal diet containing stevia leaves extract at 0.2 and 0.5 % respectively.   At the end of the experimental period (6 weeks), rats were sacrificed and blood samples were collected to obtain serum. The results indicated that, STZ treated rats showed significant increase in glucose levels compared to normal rats. Supplementation with different levels of olive leaves and stevia leaves in the diet caused significant decrease (P<0.05) in the concentration of glucose level compared to the positive control one. It was also observed that the concentration of serum lipid profile, liver functions and kidney functions were significantly improved for all tested groups, compared to the positive control group. In conclusions, diet supplemented olive leaves and stevia leaves caused an improvement of the biochemical results from diabetes, therefore olive leaves and stevia leaves could be used as a suitable supplementation therapy for diabetic patients.

DOI

10.21608/jsezu.2022.253039

Keywords

diabetes, Olive leaves, stevia leaves, glucose

Authors

First Name

Mohamed

Last Name

S. Abd El-Baky

MiddleName

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Affiliation

Nutrition and Food Science Dept., Faculty of Home Economics, Helwan University

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Orcid

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First Name

Eid

Last Name

A. Zaki

MiddleName

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Affiliation

Faculty of specific education, Banha University

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City

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Orcid

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First Name

Mayada

Last Name

S. El Haggar

MiddleName

-

Affiliation

Nutrition and Food Science Dept., Faculty of Home Economics, Helwan University

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Volume

8

Article Issue

2

Related Issue

34108

Issue Date

2022-04-01

Receive Date

2022-08-04

Publish Date

2022-04-01

Page Start

647

Page End

675

Print ISSN

2356-8690

Link

https://jsezu.journals.ekb.eg/article_253039.html

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https://jsezu.journals.ekb.eg/service?article_code=253039

Order

253,039

Type

المقالة الأصلية

Type Code

2,139

Publication Type

Journal

Publication Title

مجلة دراسات وبحوث التربية النوعية

Publication Link

https://jsezu.journals.ekb.eg/

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Article

Created At

23 Jan 2023