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208807

Nursing Interventions for Hepatitis C Elderly Patients to Reduce the Side Effects of Pegylated Interferon and Ribavirin and Improve their Quality of Life

Article

Last updated: 28 Dec 2024

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Abstract

Side effects from hepatitis C treatment can be uncomfortable, sometimes debilitating
and rarely even life-threatening for elderly people. With the right planning and support,
many of these side effects can be managed which will help in complying with the treatment
and in turn improve the quality of life. Objective: To identify the effect of nursing intervention
for hepatitis C elderly patients to reduce the side effects of pegylated interferon and ribavirin
and improve their quality of life. Setting: The study was carried out at the outpatient clinics
of the Specialized Medical Hospital, the General Mansoura Hospital, and the Egyptian Liver
Hospital in Dakahlia. Subjects: The study comprised 66 elderly patients with HCV divided
into two equal groups of 33 each. Tools: Data was collected using six tools: an interview
schedule sheet to assess the socio-demographic and health profile of elders, the short form-36
health survey questionnaire, a checklist to identify medication side effects, fatigue severity
scale, geriatric depression scale and nursing intervention program. Results: The main side
effects from treatment as reported by the elderly were fatigue, insomnia, bone ache, heart
burn, fever, itching and stomatitis respectively. Elderly patients in the study group showed
significant improvement in their ratings of perceived fatigue at both 8 and 12 weeks post
intervention, while fatigue level for those in the control group did not show any significant
change in both evaluations. As well significance improvement in the quality of life post 12
week of intervention in study group was observed. Conclusion: It can be concluded that the
side effects and quality of life mean scores improved significantly in the study group
compared to control group after 8 and 12 weeks of nursing intervention. Recommendations:
Caregivers of elders undergoing hepatitis C treatment should support, motivate and
encourage elders to cope with side effects of the hepatitis C therapy.

DOI

10.21608/asalexu.2014.208807

Keywords

side effects, quality of life, Pegylated Interferon and Ribavirin, Elderly

Authors

First Name

Raefa

Last Name

Alam

MiddleName

-

Affiliation

Gerontological Nursing, Faculty of Nursing, Mansoura University

Email

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City

-

Orcid

-

First Name

Doaa

Last Name

Fadila

MiddleName

El-Sayed

Affiliation

Gerontological Nursing, Faculty of Nursing, Mansoura University

Email

-

City

-

Orcid

-

First Name

Gamal

Last Name

Shiha

MiddleName

El-Sayed

Affiliation

Internal Medicine; GIT and liver unit, Faculty of Medicine, Mansoura University

Email

-

City

-

Orcid

-

Volume

16

Article Issue

2

Related Issue

29304

Issue Date

2014-12-01

Receive Date

2021-12-11

Publish Date

2014-12-01

Page Start

119

Page End

144

Print ISSN

1687-3858

Link

https://asalexu.journals.ekb.eg/article_208807.html

Detail API

https://asalexu.journals.ekb.eg/service?article_code=208807

Order

208,807

Type

Research articles

Type Code

2,129

Publication Type

Journal

Publication Title

Alexandria Scientific Nursing Journal

Publication Link

https://asalexu.journals.ekb.eg/

MainTitle

Nursing Interventions for Hepatitis C Elderly Patients to Reduce the Side Effects of Pegylated Interferon and Ribavirin and Improve their Quality of Life

Details

Type

Article

Created At

23 Jan 2023