Caring of the mechanically ventilated patients is a fundamental component of the nurse's
clinical practice in the intensive care units (ICUs). Clustered nursing interventions are defined as
group of interventions more than six interventions for every patient in one nursing interaction.
Physiological responses may be an immediate response or long term effects of one or more of the body
systems related to physiological condition and therapeutic interventions. Critical care nurses monitor
patient's physiological parameters on a regular basis to assure the patient's stability. Objective:
Determine physiological responses related to clustered nursing interventions among mechanically
ventilated patients. Setting: The ICUs of the Alexandria main university hospital and the General ICU
of Damanhur Medical National Institute Hospital. Subjects: A convenience sampling of 80 adult
mechanically ventilated patients. Tools: Two tools were used to collect the data of this study. Tool
one: "Physiological Response Measurement" and tool two: "Clustered Nursing Interventions
Assessment Record. Results: A significant relation between mean physiological responses and
clustered nursing care. Conclusion: Most of the physiological responses were affected significantly by
the number of clustered nursing interventions, other are indicated by mean respiratory rate, mean
systolic blood pressure and mean oxygen saturation. Recommendations: Continuous monitoring of
the physiological responses during clustered nursing care performance. On-clustered nursing
interventions should be performed and applied in the ICUs to prevent physiological response
alterations related to clustered nursing interventions performance.