Background: In the health-care system, motivation is crucial for retaining healthcare workers. As a result, health-care systems become more productive, which is reflected in patient outcomes. In the nursing profession, there are various motivating patterns to consider, including rewards, relationships, challenges, control, and drive. Patient satisfaction, quality of life, symptoms, morbidity, and mortality are only a few of the health-care service's patient outcomes. Aim: To assess relation between nurses' motivation and patients' satisfaction in dialysis units. Research design: Cross sectional descriptive correlative research design. Subjects: Convenience sample, the study subjects were including nurses and patients in dialysis units with total number 447patients and 83 nurses. Setting: The study was conducted at Dialysis Units of: Minia General Hospital, Minia University Hospital and Health Insurance Hospital. Tools of data collection: included two tools; first tool Motivation factors of nurses; second tool Patient's satisfaction. Results: the majority of staff nurses (89.2%) have moderate level of motivational factors in selected Hospitals, while (10.8%) of them has high level of motivational factors. Moreover the majority of patients (66%) have moderate level of satisfaction in selected Hospitals, while (34%) of them has high level of satisfaction. Conclusion: The findings of this study revealed that positive correlation between nurses' Motivation factors and patients' satisfaction in selected Hospitals. Recommendations: The hospital should establish multidisciplinary motivation teams which will be responsible for care of the careers. The team would also be responsible in conducting meetings and facilitate in exploring other means of motivating the nurses. Moreover the nursing care should continually involve the patients in their care in order to individualize the care.