Background: Nurses spend several hours a day in work environment; thus, quality of work life and organizational commitment are two important components for the staff, and dissatisfaction of these issues affects their other roles at home and community. The Work Life balance must be maintained effectively to ensure that all employees are working at their peak potential and free from stress. Aim: To assess the relation between quality of Nursing work life and organizational commitment. Research design: A descriptive cross- sectional research design. Subjects: A representative sample 30% of total staff nurses (N= 193). Setting: Chest Diseases Hospital, at Kuwait. Tools of data collection: included two tools; first tool Brook's Quality of Nursing Work Life Survey; second the Organizational Commitment of the Staff Nurses Questionnaire. Results: More than half of staff nurses (57.0%) had the moderate level to the total quality of work life. Most staff nurses (86.5%) had a moderate level of total organizational commitment. There were positive fair association between total organizational commitment of the staff nurses and their work life, work design, work context, work world, and total quality of nursing work life. Also, there were positive association between total quality of nursing work life of staff nurses and their affective, continuance and normative commitment. Conclusion: The findings of this study revealed that quality of nursing work life and organizational commitment were positively correlated. Recommendation: Increase nurses' satisfaction through competitive salaries, encourage the teamwork spirit and conduct periodical meetings to discuss their problems.